DL-Dithiothreitol CAS 3483-12-3 DTT

Dithiothreitol is a commonly used reducing agent, also known as dimercaptothreitol (DTT for short), with strong reducing power, which is largely due to the conformational stability of its oxidation state six-membered ring (containing disulfide bonds).The reducing power is affected by the pH value, only in the case of pH value greater than 7 can play a reducing effect.This is due to the fact that only the deprotonated thiol salt anion (-S-) is reactive, the thiol (-SH) is not; and the pKa of the mercapto group is typically ∼8.3.

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Model:
3483-12-3
Brand:
Futurechemical
Code:
3483-12-3

Product Description

DL-Dithiothreitol Basic information
Product Name:	DL-Dithiothreitol
CAS:	3483-12-3
MF:	C4H10O2S2
MW:	154.25
EINECS:	222-468-7
Mol File:	3483-12-3.mol
DL-Dithiothreitol Chemical Properties
Melting point	41-44 °C(lit.)
Boiling point	125 °C
alpha	-0.2～+0.2°(20℃/D)(c=5,H2O)
bulk density	300kg/m3
density	1.04 g/mL at 20 °C
vapor density	5.3 (vs air)
vapor pressure	0.019-0.29Pa at 20-50℃
refractive index	1.5200 (estimate)
Fp	>230 °F
storage temp.	-20°C (or 4°C short term).
solubility	H2O: 50 mg/mL, clear, colorless
form	Powder
pka	pK1:8.9 (25°C)
color	White
PH	4.0-6.0 (20-25℃, 0.1m in H2O)
Odor	Unpleasant Odor
PH Range	4 - 6 at 15,4 g/l at 25 °C
biological source	synthetic
Water Solubility	freely soluble
Sensitive	Air Sensitive
λmax	λ: 260 nm Amax: 0.400
λmax	λ: 280 nm Amax: 0.100
Merck	143,376
BRN	1719757
Stability:	Stability Stable, but heat sensitive. Incompatible with strong oxidizing agents. Keep frozen at -20 to -10 C.
InChIKey	VHJLVAABSRFDPM-UHFFFAOYSA-N
LogP	0.07 at 25℃ and pH5
CAS DataBase Reference	3483-12-3(CAS DataBase Reference)
NIST Chemistry Reference	2,3-Butanediol, 1,4-dimercapto-, (r,r)-(3483-12-3)
EPA Substance Registry System	1,4-Dithiothreitol (3483-12-3)
Absorption	cut-off at 330nm

DL-Dithiothreitol CAS 3483-12-3 DTT C4H10O2S2 Protein reducing agent Enzyme activity maintainer

Quality Assurance

Full-Process Quality Control: From incoming raw material inspection to in-process monitoring and final outgoing checks, every batch is inspected at each production stage against strict acceptance standards.
Third-Party Certified & Tested: Our quality management system is certified to ISO 9001, and products are regularly tested by accredited laboratories (e.g. SGS, TÜV). Test reports are available on request.
100% Batch Traceability: Each batch carries a unique lot number that links raw material records, production parameters, and test results, enabling complete traceability from factory to final delivery.
Pre-Shipment Inspection: Every order passes a final pre-shipment inspection, with inspection photos and reports shared before dispatch.

FAQ From Customers

Q1: What is the minimum order quantity?

A: There is no quantity limit for the first sample or trial order. Just tell us the actual quantity you need.
Q2: How can I confirm that the quality meets the requirements?

A: Provide your specifications, and our technical team will check them or customize them for you; we can provide TDS, MSDS, and COA, and accept third-party testing.
Q3: How do you ensure stable quality?

A: We manufacture under an ISO 9001 quality system, test every batch before release, and retain samples for 24 months for traceability.
Q4: Do you provide samples?

A: Yes — Free samples are available; freight is at buyer's expense for express delivery.