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HEPES sodium salt HEPES-NA 75277-39-3

N-(2-hydroxyethyl)piperazine-N'-(2-ethanesulfonic acid), or HEPES, is one of the best buffers for all biological studies. HEPES is a zwitterionic organic chemical buffer at most physiological pHs, which is one of Good's buffer reagents, and has the strongest buffering capacity in the pH range of 6.0-8.5.
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  • 75277-39-3

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  • 75277-39-3

HEPES sodium salt Basic information
Product Name: HEPES sodium salt
CAS: 75277-39-3
MF: C8H19N2NaO4S
MW: 262.3
EINECS: 278-169-7
Mol File: 75277-39-3.mol
HEPES sodium salt Chemical Properties
Melting point 234 °C
density 1.504[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. room temp
solubility H2O: 1 M at 20 °C, clear, colorless
form dry powder
color White
PH 10.0-12.0 (1M in H2O)
PH Range 6.8 - 8.2
pka 7.5(at 25℃)
biological source synthetic
Water Solubility It is soluble in water.
Sensitive Hygroscopic
Stability: Stable. Hygroscopic - protect from moisture. Incompatible with strong oxidizing agents.
CAS DataBase Reference 75277-39-3(CAS DataBase Reference)
EPA Substance Registry System 1-Piperazineethanesulfonic acid, 4-(2-hydroxyethyl)-, monosodium salt (75277-39-3)
Absorption ≤0.2 at 260 in H2O at 1M
≤0.2 at 280 in H2O at 1M

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