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Pharma grade 99% TRIS hydrochloride CAS 1185-53-1 Tris(hydroxymethyl)aminomethane hydrochloride

Synonyms:Tris(hydroxymethyl)aminomethane hydrochloride
2-Amino-2-(hydroxymethyl)propane-1,3-diol hydrochloride
Tris-HCL
Tris.HCl
Molecular Formula:C4H12ClNO3
Molecular Weight: 157.6
HS Code: 2922199090
Grade:Pharma grade 99%
Hazard Class:General Cargo

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Model:
1185-53-1
Brand:
futurechem
Code:
1185-53-1

Product Description

Certificate of Analysis-COA

SPECIFICATION PROPERTIES	STANDARD	RESULT
Appearance	White crystalline powder	White crystalline powder
Assay, %	99.0~101.0%	99.87%
Loss on drying	≤1%	0.26%
Solubility (20% H₂O)	Colorless, clear	Colorless, clear
pH (0.5M aqueous)	3.5–5.0	4.18
Heavy metals (as Pb), ppm	≤5	≤5
UV Absorbance (1M in H₂O) A260nm	≤0.06	0.009
UV Absorbance (1M in H₂O) A280nm	≤0.05	0.005
Conclusion	—	Qualified

Applications

1. Molecular Biology Buffers The standard buffer component for DNA/RNA electrophoresis, PCR and immunoassay systems. Maintains stable pH (7.0-9.0) with high buffering capacity, delivering reproducible results in molecular biology workflows.

2. Protein Purification & Chromatography A reliable buffer salt for protein purification, chromatography and electrophoresis applications. Low UV absorbance and consistent ionic strength minimize interference in detection and separation steps.

3. Diagnostic & IVD Reagents A trusted buffer for in-vitro diagnostic reagent kits and clinical assays. High purity and low metal ion content ensure stable, accurate assay performance.

4. Cell Culture & Biotechnology Maintains physiological pH in cell culture media and bioprocessing applications. High purity grades support reproducible cell growth and product consistency in biotech production.

5. Industrial & Cosmetic Applications Used as a pH buffer and stabilizer in industrial and cosmetic formulations. Stable quality and broad compatibility support reliable performance across diverse applications.

Production Line

We operate 10+ production lines, backed by a well-stocked raw material warehouse.

Our workshop is equipped with automated machinery — ensuring high consistency and precision on every order, from trial samples to full container loads.

Every order follows a standardized workflow. Key quality control points are set at every stage.

Factory Area

Standardized Process Flow

Production Capacity

Located in Shandong, our factory is approximately 300km from Qingdao Port, enabling fast and cost-effective delivery to customers worldwide.

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Quality Assurance

Full-Process Quality Control: From incoming raw material inspection to in-process monitoring and final outgoing checks, every batch is inspected at each production stage against strict acceptance standards.
Third-Party Certified & Tested: Our quality management system is certified to ISO 9001, and products are regularly tested by accredited laboratories (e.g. SGS, TÜV). Test reports are available on request.
100% Batch Traceability: Each batch carries a unique lot number that links raw material records, production parameters, and test results, enabling complete traceability from factory to final delivery.
Pre-Shipment Inspection: Every order passes a final pre-shipment inspection, with inspection photos and reports shared before dispatch.

FAQ From Customers

Q1: What is the minimum order quantity?

A: There is no quantity limit for the first sample or trial order. Just tell us the actual quantity you need.
Q2: How can I confirm that the quality meets the requirements?

A: Provide your specifications, and our technical team will check them or customize them for you; we can provide TDS, MSDS, and COA, and accept third-party testing.
Q3: How do you ensure stable quality?

A: We manufacture under an ISO 9001 quality system, test every batch before release, and retain samples for 24 months for traceability.
Q4: Do you provide samples?

A: Yes — Free samples are available; freight is at buyer's expense for express delivery.