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Meglumine CAS 6284-40-8

Choosing a suitable equilibrium ion for meglumine as a drug is particularly important for improving its solubility and bioavailability. Glucosamine (N-methyl-D-glucosamine) is a widely used equilibrium ion to enhance drug solubility. It is an amino sugar derived from sorbitol, with a pKa value of 9.6.
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  • 6284-40-8

  • futurechemical

  • 6284-40-8

Meglumine Basic information

Product Name:

Meglumine

CAS:

6284-40-8

MF:

C7H17NO5

MW:

195.21

EINECS:

228-506-9

Mol File:

6284-40-8.mol

Meglumine Chemical Properties

Melting point

129-131.5 °C (lit.)

alpha

-16.5 º (c=10, H2O, on dry sub)

Boiling point

331.88°C (rough estimate)

density

1.2669 (rough estimate)

bulk density

300kg/m3

RTECS

LZ4295770

refractive index

-16.5 ° (C=2, H2O)

storage temp.

2-8°C

solubility

H2O: 0.1 g/mL, clear, colorless

form

Crystalline Powder

pka

pKa 9.39(H2O,t =30.0,I=0.05N2)(Approximate)

color

White to almost white

PH

11 (10g/l, H2O, 20℃)

Optical Rotation

[α]20/D 16.5±0.5°, c = 2% in H2O

biological source

synthetic (organic)

Water Solubility

100 g/100 mL (25 ºC)

Sensitive

Air Sensitive & Hygroscopic

Merck

146,078

BRN

385906

Major Application

pharmaceutical (small molecule)

Cosmetics Ingredients Functions

HAIR CONDITIONING

InChI

1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1

InChIKey

MBBZMMPHUWSWHV-VZFHVOOUSA-N

SMILES

CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO

LogP

-3.370 (est)

NIST Chemistry Reference

N-methylglucamine(6284-40-8)

EPA Substance Registry System

Meglumine (6284-40-8)

通用.jpg
固体.jpg

Items

Specification

Results

Characteristics

White or off-white crystalline powder

Conforms

Solubility

Freely soluble in water, sparingly

Complies

Identification

soluble in ethanol

Complies

Melting point

Complies

128-129°C

Specific rotation

128-132°C

-16.4°

Clarity and color of solution

-15.7-17.3°

Complies

Loss on drying

Solution should be clarified

0.002

Residue on ignition

Absorbance(420nm)<0.03(20%w/v)

0.04%

Heavy metals

<0.5%

0.04%

Reducing substance

<0.1%

<10ppm

Assay

≤10ppm

Complies

Conclusion

Complies with In-house/USP-NF202l standard

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    Full-Process Quality Control: From incoming raw material inspection to in-process monitoring and final outgoing checks, every batch is inspected at each production stage against strict acceptance standards.
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FAQ From Customers
  • Q1: What is the minimum order quantity?
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    A: There is no quantity limit for the first sample or trial order. Just tell us the actual quantity you need.
  • Q2: How can I confirm that the quality meets the requirements?
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    A: Provide your specifications, and our technical team will check them or customize them for you; we can provide TDS, MSDS, and COA, and accept third-party testing.
  • Q3: How do you ensure stable quality?
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    A: We manufacture under an ISO 9001 quality system, test every batch before release, and retain samples for 24 months for traceability.
  • Q4: Do you provide samples?
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    A: Yes — Free samples are available; freight is at buyer's expense for express delivery.
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